HiPP, with their brand COMBIOTIC®, uses the probiotic culture L. fermentum®, which was originally isolated from breast milk, and the prebiotic galacto-oligosaccharides (GOS), which are derived from lactose. The combination of both ingredients was investigated by two separate studies and both their safety and their benefit were confirmed. The proven benefit of infant as well as follow-on formulae was the significant reduction of gastrointestinal infections when compared to the control group.